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Iron hydroxide adipate tartrate (IHAT) is a novel oral iron supplement developed as a ferritin mimetic. It consists of a nano-Fe(III) core doped with tartrate salt in an adipate buffer, designed to mimic the structure and absorption profile of dietary ferritin. IHAT is well absorbed in the gut and preserves the gut microbiome compared to traditional iron supplements. Its primary indication is for the treatment of iron deficiency anemia. The drug is being developed by Nemysis and has reached Phase III clinical trials for this indication[1][2][4][5][8].
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