Drug intelligence / Profile preview

iron sucrose + epoetin

Development stage
Unknown
Lead developer
CSL Vifor
Modality
Small Molecules, Recombinant Proteins and Enzymes
Administration
Intravenous, Subcutaneous, Parenteral
01

Overview

This combination therapy consists of iron sucrose, a parenteral iron replacement, and epoetin, a recombinant human erythropoiesis-stimulating agent (ESA). Iron sucrose, developed by Vifor Pharma (now CSL Vifor) under the brand name Venofer, provides a source of iron for hemoglobin synthesis. Epoetin acts as an agonist at the erythropoietin receptor, stimulating the proliferation and differentiation of red blood cell precursors in the bone marrow. The co-administration of these agents is a standard clinical approach to managing anemia, particularly in patients with chronic kidney disease (CKD) or in preterm infants (anemia of prematurity), where both iron deficiency and insufficient endogenous erythropoietin production may be present.

Other names
Vifor + epoetiniron sucrose + erythropoietinVenofer + epoetin
02

Targets

Erythropoietin Receptor

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