irvingia gabonensis extract

Irvingia gabonensis extract, commonly known as African mango, is a botanical extract derived from the seeds of the West African tree *Irvingia gabonensis*. It is primarily utilized as a dietary supplement for weight management and metabolic health. The most clinically studied standardized version is IGOB131. The extract contains active polyphenolic compounds, including ellagic acid and its derivatives. Its mechanism of action involves the modulation of adipogenesis and lipid metabolism by down-regulating the expression of peroxisome proliferator-activated receptor gamma (PPARγ) and leptin genes, while up-regulating adiponectin. Clinical trials have investigated its efficacy in treating obesity, metabolic syndrome, and hyperlipidemia, though evidence quality is often cited as limited due to methodological concerns.

Brand names

Integra-Lean African Mango IrvingiatruDERMA MangodrinVitacost African Mango Extract IGOB131 Certified

Other names

African mango extractIrvingia gabonensis seed extractDika nut extractOgbono