irvingia gabonensis seed extract

IGOB131 is a patented and standardized seed extract derived from the West African plant *Irvingia gabonensis*, commonly known as African mango. It is primarily used as a dietary supplement for weight management and metabolic wellness. Clinical studies have shown that IGOB131 can significantly reduce body weight, waist circumference, and body fat in overweight or obese individuals. The mechanism of action involves modulation of key metabolic pathways related to adipogenesis—specifically impacting PPAR gamma activity, increasing adiponectin levels (which enhances energy balance and reduces fat cell size), decreasing leptin (regulating appetite and satiety), lowering C-reactive protein (a marker of inflammation), improving cholesterol profiles (total cholesterol and LDL cholesterol), reducing blood glucose levels, and inhibiting the enzyme glycerol-3-phosphate dehydrogenase involved in fat storage[2][3][4][7]. The ingredient is generally well-tolerated with mild side effects such as flatulence or headache reported at rates similar to placebo[1][2]. It has been granted U.S. FDA GRAS status.

Brand names

WellTrim iGIGOB131IGOB-131IGOB 131

Other names

African mango extractirvingia gabonensis seed extractIGOB131IGOB-131IGOB 131