Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
ISLA-6181
- Development stage
- Preclinical
- Lead developer
- Island Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
ISLA-6181 is a small molecule antiviral candidate being developed by Island Pharmaceuticals (formerly Isla Pharmaceuticals). Currently in the IND-enabling stage, it is characterized as a host-targeting antiviral (HTA) designed to treat various viral infections, potentially including flaviviruses such as Dengue and Zika. As a next-generation HTA, it aims to inhibit host cell proteins that viruses exploit for replication, thereby providing a broad-spectrum therapeutic approach with a higher barrier to viral resistance compared to direct-acting antivirals. The drug's mechanism involves blocking the nuclear transport of viral proteins, which prevents the virus from suppressing the host's innate immune response.
- Other names
- ISLA-6181ISLA6181ISLA 6181
02
Targets
NS5 (Flavivirus nonstructural protein 5)Importin alpha/beta1 heterodimer
Beyond the preview
Go deeper on ISLA-6181.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on ISLA-6181.