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ISO 24444:2010 P2 Standard Reference Sunscreen is a standardized formulation used as a control in clinical trials to determine the Sun Protection Factor (SPF) of topical products. Defined by the International Organization for Standardization (ISO) under the 24444:2010 protocol, the P2 formulation serves as a benchmark to ensure the accuracy and reproducibility of SPF testing across different laboratories and participants. It is an oil-in-water emulsion containing a specific combination of UV filters, including homosalate, octinoxate, and oxybenzone. In clinical evaluations conducted by GlaxoSmithKline, it is utilized as an intra-individual comparator to validate the SPF efficacy of consumer products, such as ChapStick Moisturizer lip balms, against a known reference standard.
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