isobutyl cyanoacrylate

Isobutyl cyanoacrylate is a medical-grade tissue adhesive and surgical glue. It is a cyanoacrylate ester that undergoes rapid polymerization upon contact with moisture or ionic surfaces (such as blood or tissue fluids), forming a strong physical bond that seals wounds and joins tissues. It is valued for its waterproof and bacteriostatic properties, which aid in surgical wound closure and the prevention of infection. While historically used in various surgical applications, including the repair of urethrocutaneous fistulas (UCF) and the embolization of vascular malformations, it is chemically distinct from other cyanoacrylates like n-butyl or isoamyl cyanoacrylate. Notably, the clinical trial context provided (NCT04876976) by Ain Shams University evaluates the related compound **isoamyl 2-cyanoacrylate** (Amident) as an interposition layer in UCF repair following hypospadias surgery, rather than the isobutyl derivative specified in the input name.

Brand names

Bucrylate

Other names

isobutyl 2-cyanoacrylateisobutyl2-cyanoacrylateisobutyl-2-cyanoacrylate2-methylpropyl 2-cyanoacrylatecyanoacrylate + isobutyl