Drug intelligence / Profile preview

Isologic Pyrophosphate

Development stage
Unknown
Lead developer
Isologic Innovative Radiopharmaceuticals
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

Isologic Pyrophosphate is a radiopharmaceutical "cold kit" developed and distributed by Isologic Innovative Radiopharmaceuticals. The kit contains a non-radioactive pyrophosphate reagent intended for reconstitution and labeling with technetium-99m (Tc-99m) to form Technetium Tc 99m Pyrophosphate. Once labeled, the agent is administered intravenously for diagnostic nuclear medicine imaging. It is primarily utilized in cardiac imaging, specifically for the detection and localization of acute myocardial infarction and the non-invasive diagnosis of transthyretin cardiac amyloidosis (ATTR-CA), where the radiopharmaceutical localizes in areas of abnormal calcium metabolism or amyloid deposition. The product is marketed as a room-temperature stable kit, improving accessibility for diagnostic procedures across Canada.

Brand names
Isologic PyrophosphateTrousse Isologic d'injection de pyrophosphate
Other names
Pyrophosphate Injection KitTechnetium Tc 99m Pyrophosphate Kit
02

Targets

TTR amyloid fibril (Transthyretin amyloid fibril)

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