Isopropamide

Isopropamide is a long-acting quaternary ammonium anticholinergic (antimuscarinic) drug. It acts as an antagonist at muscarinic acetylcholine receptors, particularly the M3 subtype, thereby inhibiting the action of acetylcholine on smooth muscle and glandular tissue. This results in reduced gastrointestinal motility and secretion. Isopropamide was discovered by Janssen Pharmaceutica in 1954 and has been used primarily for the treatment of peptic ulcers and other gastrointestinal disorders characterized by hyperacidity or hypermotility, such as irritable bowel syndrome and nervous dyspepsia. It may also be used to relieve symptoms associated with colds or rhinitis due to its peripheral antimuscarinic effects similar to those of atropine[1][3][4][5].

Other names

isopropamide iodideisopropamide bromideisopropamide chloride