Drug intelligence / Profile preview

isopropyl alcohol + methylprednisolone acetate + lidocaine

Development stage
Unknown
Lead developer
Amneal Pharmaceuticals
Modality
Small Molecules
Administration
Intramuscular, Intraarticular, Intralesional
01

Overview

A marketed **combination injection kit** containing **methylprednisolone acetate**, a depot glucocorticoid corticosteroid; **lidocaine**, a local anesthetic; and **isopropyl alcohol**, an antiseptic skin-preparation component. The therapeutic activity is driven primarily by methylprednisolone acetate, which acts as a **glucocorticoid receptor agonist** to suppress inflammatory and immune signaling, while lidocaine provides local anesthesia and isopropyl alcohol is used for procedural antisepsis. Based on the provided context, this kit is manufactured by **Amneal Pharmaceuticals** and is used around intramuscular, intra-articular, soft tissue, and intralesional administration settings for inflammatory and rheumatologic disorders such as acute gouty arthritis, bursitis, tenosynovitis, epicondylitis, rheumatoid arthritis, and synovitis of osteoarthritis, as well as selected intralesional dermatologic conditions including alopecia areata, discoid lupus erythematosus, keloids, granuloma annulare, lichen planus, lichen simplex chronicus, psoriatic plaques, and necrobiosis lipoidica diabeticorum.

Brand names
Dyural L KitDyural 40 KitDyural40 KitDyural-40 KitDyural 80 KitDyural80 KitDyural-80 KitMulti-Specialty Kit
Other names
isopropyl alcohol + methylprednisolone acetate + lidocaine hydrochloride
02

Targets

GR (Glucocorticoid receptor)NaV (Voltage-gated sodium channels)

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