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isopropyl alcohol + povidone iodine
- Development stage
- Unknown
- Lead developer
- Becton Dickinson
- Modality
- Implantable Devices → Device-based Delivery → Drug Delivery Systems, Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
- Administration
- Topical
01
Overview
Isopropyl alcohol + povidone iodine is a topical antiseptic combination used primarily for skin disinfection before surgical procedures or injections. This formulation leverages the rapid antimicrobial action of isopropyl alcohol and the broad-spectrum, persistent activity of povidone-iodine. The combination provides a synergistic effect—acting faster and with a broader spectrum than povidone-iodine alone, while offering more persistent antimicrobial activity than isopropyl alcohol alone. It works by denaturing proteins (isopropyl alcohol) and releasing free iodine to disrupt microbial cell structures (povidone-iodine). This combination reduces bacterial load on the skin to prevent infection at surgical or injection sites[1][3][8].
- Brand names
- LorisSoluprep
- Other names
- isopropyl alcohol and povidone-iodinePVP-I with isopropyl alcohol
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