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ITF3912 is a peptide-drug conjugate (PDC) being developed by Italfarmaco for the treatment of solid tumors. As a PDC, it is designed to selectively deliver a cytotoxic payload to tumor cells by utilizing a peptide ligand that targets specific receptors or proteins overexpressed on the surface of cancer cells. This targeted approach aims to enhance the therapeutic index of the cytotoxic agent while minimizing systemic toxicity. Currently, the drug is in the IND-enabling stage of development, and its specific molecular target and payload components have not been publicly disclosed.
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