Drug intelligence / Profile preview

Itnogen

Development stage
Phase 3
Lead developer
Kyowa Kirin International
Modality
Small Molecules
Administration
Transdermal
01

Overview

**Itnogen** is a 20 mg/g (2%) transdermal testosterone gel formulation used as testosterone replacement therapy in adult men with male hypogonadism, confirmed by two separate blood testosterone measurements and clinical symptoms such as impotence, infertility, low sex drive, tiredness, depressive moods, and bone loss. The active ingredient, testosterone, is an androgen hormone responsible for male sex organ development and secondary sex characteristics. Applied topically once daily to the abdomen or inner thighs via a metered-dose pump (starting dose 3 g gel containing 60 mg testosterone, adjustable up to 4 g/80 mg), it restores serum testosterone to normal levels (300-1140 ng/dL) while minimizing risks like skin transfer to others.[1][4][6]

Brand names
ItnogenTostranFortigelTostrex
Other names
ARD-0403ARD0403ARD 0403
02

Targets

AR (Adrenergic receptors)

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