Drug intelligence / Profile preview

ITOP5

Development stage
Preclinical
Lead developer
Infinitopes
Modality
Peptides, Vaccines & Immunotherapeutics
Administration
Subcutaneous, Intramuscular
01

Overview

ITOP5 is a preclinical-stage, off-the-shelf peptide-based cancer vaccine being developed by Infinitopes. It is designed to target specific tumor-associated antigens to stimulate a T-cell-mediated immune response against cancer cells. As part of Infinitopes' pipeline, ITOP5 is currently being evaluated for an undisclosed cancer indication (referred to as indication #5). The vaccine utilizes the company's proprietary antigen discovery platform to identify high-confidence targets that are shared across patient populations, enabling an off-the-shelf therapeutic approach.

02

Targets

pMHC-I (Peptide–MHC class I complex)

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