Drug intelligence / Profile preview

ITZ-DerMap

Development stage
Preclinical
Lead developer
ArrayPatch
Modality
Small Molecules
Administration
Topical
01

Overview

ITZ-DerMap is a proprietary microneedle patch delivery system for the antifungal drug itraconazole, developed by ArrayPatch, a spin-out from University College Cork. It is specifically designed for the treatment of onychomycosis (fungal nail infection). The patch utilizes microneedle technology to penetrate the nail plate and deliver the active pharmaceutical ingredient directly to the site of infection in the nail bed. This localized delivery approach aims to improve efficacy while avoiding the systemic side effects and drug-drug interactions typically associated with oral itraconazole therapy, such as hepatotoxicity.

Brand names
ITZ-DerMap
Other names
Itraconazole microneedle patch
02

Targets

CYP51A1 (Sterol 14α-demethylase)

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