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IVIEW-1502
- Development stage
- Phase 4
- Lead developer
- IVIEW Therapeutics
- Modality
- Small Molecules, Hydrogel Systems → Drug Delivery Systems
- Administration
- Intranasal, Topical
01
Overview
IVIEW-1502 is an investigational in-situ gel-forming nasal formulation combining povidone-iodine (PVP-I) and budesonide for the treatment of chronic rhinosinusitis (CRS). Developed by IView Therapeutics in collaboration with Dr. Amin Javer, the formulation is designed as a long-acting nasal spray that utilizes a polysaccharide gel matrix to prolong drug retention in the nasal cavity. Upon contact with nasal mucus ions, the suspension undergoes a solution-to-gel phase transition, which increases residence time and reduces mucociliary clearance. Povidone-iodine acts as a broad-spectrum antiseptic with antibacterial and antifungal properties to address potential infectious components, while budesonide serves as a corticosteroid to reduce underlying inflammation. The drug is primarily intended for use following endoscopic sinus surgery (ESS) to improve postoperative healing and endoscopic outcomes in adult patients with CRS.
- Other names
- PVP-I/Budesonide GelPovidone-Iodine and Budesonide Gel-Forming SuspensionIntra-sinus Povidone-iodine/Budesonide Gel
02
Targets
GR (Glucocorticoid receptor)
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