Drug intelligence / Profile preview

IVIEW-1701

Development stage
Unknown
Lead developer
IVIEW Therapeutics
Modality
Hydrogel Systems → Drug Delivery Systems, Small Molecules
Administration
Ophthalmic
01

Overview

IVIEW-1701 is an ophthalmic in-situ gel formulation of bromfenac sodium, a non-steroidal anti-inflammatory drug (NSAID), developed by IVIEW Therapeutics. It utilizes the proprietary i-Gel technology, a drug delivery platform that transforms from a liquid solution to a gel upon contact with the ocular surface, triggered by factors such as pH, ionic concentration, or temperature. This sustained-release formulation is designed to provide prolonged therapeutic levels of bromfenac in the eye, potentially allowing for once-daily dosing to manage inflammation and pain following ocular surgeries, such as cataract extraction. By inhibiting cyclooxygenase enzymes, IVIEW-1701 reduces the synthesis of prostaglandins that mediate the inflammatory response and pain signaling in ocular tissues.

Other names
Bromfenac i-GelBromfenac sodium i-Geli-Gel Bromfenac
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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