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IVX-121
- Development stage
- Unknown
- Lead developer
- Icosavax
- Modality
- Nanoparticles → Drug Delivery Systems, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
IVX-121 is a vaccine candidate developed by Icosavax for the prevention of respiratory syncytial virus (RSV) infection. It is based on a computationally designed virus-like particle (VLP) platform technology, licensed from the University of Washington's Institute for Protein Design. The vaccine incorporates a stabilized prefusion F antigen, known as DS-Cav1 (or DC-Cav1), which was licensed from the National Institute of Allergy & Infectious Diseases (NIAID) at the National Institutes of Health (NIH). This VLP vaccine aims to elicit a protective immune response against RSV by presenting the prefusion F protein, a key target for neutralizing antibodies.
- Other names
- respiratory syncytial virus virus-like particle vaccineRSV VLP vaccine
02
Targets
HMPV F (Human metapneumovirus fusion protein)
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