Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
jabuticaba leaf oral digested fraction
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Jabuticaba leaf oral digested fraction refers to the bioactive components of *Myrciaria cauliflora* leaves that have been processed through simulated gastrointestinal digestion. This fraction is characterized by a distinct phenolic profile compared to crude extracts, containing compounds such as 3,4-dihydroxybenzoic acid and ferulic acid, alongside quercetin 3-glucoside and gallic acid. Research indicates that these digested fractions exhibit significant antiproliferative and cytotoxic effects on hepatocellular carcinoma (HepG2) cells in both 2D and 3D cultures. The mechanism involves the induction of apoptotic and necrotic cell death, inhibition of cell migration, and potent antioxidant activity against reactive oxygen species (ROS). It is primarily being investigated as a potential nutraceutical for the prevention or treatment of liver cancer.
- Other names
- digested jabuticaba leaf extractMyrciaria cauliflora leaf digested fractionjabuticaba leaf gastric fractionjabuticaba leaf intestinal fraction
Beyond the preview
Go deeper on jabuticaba leaf oral digested fraction.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on jabuticaba leaf oral digested fraction.