Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
jacaranda mimosifolia extract
- Development stage
- Preclinical
- Modality
- Small Molecules
01
Overview
Jacaranda mimosifolia extract is a botanical preparation derived from the leaves of the Jacaranda tree, currently being investigated for its potential antineoplastic and hepatoprotective properties. Research indicates that the methanolic extract exhibits anti-hepatocellular carcinoma (HCC) activity by inducing apoptosis through the upregulation of pro-apoptotic markers like p53 and Bax, while downregulating oncogenic markers such as alpha-fetoprotein (AFP) and glypican-3 (GPC3). Network pharmacology and docking studies suggest that its bioactive components, including apigenin and kaempferol, may target Prostaglandin-endoperoxide synthase 2 (PTGS2/COX-2), Epidermal Growth Factor Receptor (EGFR), and Matrix Metallopeptidase 9 (MMP9). Additionally, it has demonstrated protective effects against carbon tetrachloride-induced liver injury in animal models.
- Other names
- Jacaranda mimosifolia leaf extractmethanolic extract of Jacaranda mimosifolia
02
Targets
BAX (Apoptosis regulator BAX)EGFR (Epidermal growth factor receptor)MMP9 (Matrix metalloproteinase-9)TP53 (Cellular Tumor Antigen p53 R175H)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
Beyond the preview
Go deeper on jacaranda mimosifolia extract.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on jacaranda mimosifolia extract.