Drug intelligence / Profile preview

Janssen Research and Development DHODH compound 19

Development stage
Preclinical
Lead developer
Janssen Research & Development
01

Overview

Janssen Research and Development DHODH compound 19: sourced facts only. name: "Two lead compounds, 19 and 29, have potent biochemical and cellular DHODH activity, favorable physicochemical properties, and efficacy in a preclinical model of AML." [PMID:35925768]; target: "Two lead compounds, 19 and 29, have potent biochemical and cellular DHODH activity, favorable physicochemical properties, and efficacy in a preclinical model of AML." [PMID:35925768]; developer: "Janssen Research and Development, 1400 McKean Rd, Spring House, Pennsylvania 19477, United States." [PMID:35925768]; stage: "Two lead compounds, 19 and 29, have potent biochemical and cellular DHODH activity, favorable physicochemical properties, and efficacy in a preclinical model of AML." [PMID:35925768]

02

Targets

DHODH (Dihydroorotate dehydrogenase (quinone), mitochondrial)

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