Drug intelligence / Profile preview

japanese encephalitis vaccine (live, attenuated)

Development stage
Unknown
Lead developer
Chengdu Institute of Biological Products
Modality
Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

The SA14-14-2 live-attenuated Japanese encephalitis virus vaccine is a safe and highly effective vaccine used for active immunization against Japanese encephalitis (JE). Developed by the Chengdu Institute of Biological Products (CDIBP) in China, the vaccine is prepared by propagating the attenuated SA14-14-2 strain of the Japanese encephalitis virus (JEV) in primary hamster kidney cell cultures. It is the first JE vaccine to be prequalified by the World Health Organization (WHO) for pediatric use. Administered subcutaneously, a single dose of the vaccine provides long-term protective immunity (at least five years) in endemic areas by eliciting robust neutralizing antibody and cell-mediated immune responses.

Brand names
CD.JEVAXRS.JEV
Other names
CD-JEVAXJapanese Encephalitis Vaccine Live (SA14-14-2)Japanese encephalitis vaccine, live, attenuatedLAJEVlive attenuated Japanese encephalitis vaccinelive-attenuated Japanese encephalitis virus vaccineRS-JEVSA14-14-2 live-attenuated Japanese encephalitis virus vaccineSA-14-14-2 live-attenuated Japanese encephalitis virus vaccineSA 14-14-2 live-attenuated Japanese encephalitis virus vaccine

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