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japanese encephalitis virus vaccine + Advax
- Development stage
- Preclinical
- Lead developer
- Vaxine
- Modality
- Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
- Administration
- Intramuscular
01
Overview
Japanese encephalitis virus vaccine + Advax is a recombinant protein vaccine candidate developed by Vaxine. It consists of recombinant flavivirus antigens formulated with Vaxine's proprietary Advax adjuvant, which is based on delta-inulin. The vaccine is designed to provide broad-spectrum protection against Japanese encephalitis virus (JEV) and related flaviviruses that cause encephalitis. Preclinical data suggests that the formulation induces robust immune responses and offers cross-protection against Murray Valley encephalitis virus (MVEV), Kunjin virus, and West Nile Virus (WNV). The use of the Advax adjuvant is intended to enhance the vaccine's immunogenicity while maintaining a high safety profile.
- Other names
- JEV + AdvaxJEV/MVEV/Kunjin/West Nile cross-protective vaccine
02
Targets
JEV prM/E (Japanese encephalitis virus prM/E antigen)Kunjin virus envelope proteinMurray Valley encephalitis virus envelope proteinE (Tick-borne encephalitis virus envelope protein)
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