Drug intelligence / Profile preview

jasminum subtriplinerve ethyl acetate fraction

Development stage
Preclinical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

The jasminum subtriplinerve ethyl acetate fraction is a botanical extract derived from the aerial parts or leaves of the Vietnamese traditional medicinal herb *Jasminum subtriplinerve* Blume. It is a research-stage small molecule complex containing bioactive compounds such as phenylpropanoid glycosides, flavonoid glycosides, and triterpenes. Preclinical studies have demonstrated that this specific fraction possesses significant chemopreventive and anti-proliferative properties, particularly against breast cancer cell lines like MCF-7. Its biological activity is characterized by the elevation of Interleukin-2 (IL-2) levels and the suppression of Prostaglandin E2 (PGE2) expression in serum, suggesting an immunomodulatory and anti-inflammatory mechanism of action. It is currently being evaluated in academic research for its potential application as a functional food or therapeutic agent for cancer prevention.

Other names
Jasminum subtriplinerve EtOAc fractionEtOAc fraction of Jasminum subtriplinerve
02

Targets

IL-2 (Interleukin 2)PGE2 (Prostaglandin E2)

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