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JB-201 is a preclinical antibody drug under development by Junten Bio for the prevention of graft rejection in patients undergoing kidney transplantation from brain-dead donors. While Junten Bio is primarily known for its Induced Suppressor T cells (JB-101) platform, JB-201 represents a separate antibody-based therapeutic approach aimed at improving outcomes in deceased-donor transplants. The drug is intended to modulate the immune response to induce tolerance and reduce the reliance on long-term immunosuppressive therapy, although its specific molecular target and mechanism of action have not been publicly disclosed.
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