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JBPOS0451 is a small molecule therapeutic candidate developed by Bio-Pharm Solutions for the treatment of central nervous system (CNS) disorders. It is currently in preclinical development for indications including epilepsy, infantile spasms (IS), and pain management. The compound has been evaluated through the NIH National Institute of Neurological Disorders and Stroke (NINDS) "Red Book" program, which is part of the Anticonvulsant Screening Program (ASP). While the specific molecular target of JBPOS0451 has not been publicly disclosed, Bio-Pharm Solutions focuses on the development of metabotropic glutamate receptor (mGluR) modulators and other small molecules derived from their proprietary CNS-focused chemical library.
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