Jian Pi Jie Yu Gao

Jian Pi Jie Yu Gao is a Traditional Chinese Medicine (TCM) herbal paste formulation primarily indicated for the treatment of depressive disorders, particularly those categorized under the TCM pattern of Spleen deficiency and Liver Qi stagnation. The formulation is designed to strengthen the Spleen, regulate Qi, and resolve emotional depression. It is frequently utilized as a hospital preparation in China, most notably by the Affiliated Hospital of Shandong University of Traditional Chinese Medicine, for conditions such as post-stroke depression and functional dyspepsia with comorbid mood symptoms. The preparation involves the decoction and concentration of multiple botanical ingredients—typically including *Astragalus membranaceus*, *Atractylodes macrocephala*, and *Bupleurum chinense*—into a semi-solid oral paste. Clinical research suggests the formula may exert antidepressant effects by modulating the gut-brain axis, increasing monoamine neurotransmitter levels, and upregulating brain-derived neurotrophic factor (BDNF) expression.

Other names

健脾解郁膏Jianpi Jieyu GaoJianpi Jieyu Paste