Drug intelligence / Profile preview

Jian Spleen and Tonify Kidney Formula

Development stage
Unknown
Lead developer
Longhua Hospital Shanghai University of Traditional Chinese Medicine
Administration
Oral
01

Overview

Jian Spleen and Tonify Kidney Formula is a Traditional Chinese Medicine (TCM) compound granule developed by Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. It is designed to treat elderly patients with osteoporotic hip fractures, specifically those exhibiting the TCM syndrome pattern of spleen-kidney yang deficiency. The formula aims to promote bone healing and improve bone mineral density following Proximal Femoral Nail Antirotation (PFNA) internal fixation. As a TCM formula, it typically consists of multiple herbal ingredients intended to strengthen the Spleen and Kidney systems according to traditional theory, thereby facilitating recovery and preventing secondary fractures.

Other names
Jian Spleen and Tonify Kidney FormulaJianpi Bushen FormulaJianpi Bushen Fang
02

Targets

STAT3 (Signal Transducer and Activator of Transcription 3)PGHS-1 (Prostaglandin G/H Synthase 1)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)HSP90AA1 (Heat shock protein HSP90-alpha)EGFR T790M (Epidermal growth factor receptor T790M mutant)

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