Drug intelligence / Profile preview

jiang ju nuan wei gao

Development stage
Unknown
Lead developer
Harbin Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Jiang Ju Nuan Wei Gao is a Traditional Chinese Medicine (TCM) formulation primarily indicated for the relief of gastric discomfort, abdominal pain, and indigestion caused by "stomach cold" (a TCM diagnostic pattern). The preparation typically centers on ginger (Zingiber officinale) and tangerine peel (Citri Reticulatae Pericarpium), which are processed into a thick oral paste or electuary. Pharmacologically, the active constituents such as gingerols and flavonoids exert gastroprotective, anti-emetic, and prokinetic effects by modulating vanilloid receptors and serotonin signaling in the gastrointestinal tract. It is widely used in China as an over-the-counter remedy for chronic gastritis and functional dyspepsia characterized by cold sensitivity.

Brand names
Jiang Ju Nuan Wei Gao
Other names
Ginger and Tangerine Peel Stomach-Warming PasteJiangju Nuanwei Gao
02

Targets

TRPV1 (Transient receptor potential cation channel subfamily V member 1)HTR3A (5-hydroxytryptamine receptor 3A)

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