Jiangsu Ocean Univ. σ1R compound 67

Jiangsu Ocean Univ. σ1R compound 67: sourced facts only. name: "Among them, compound 67 demonstrated high binding affinity for both σ1R (Kᵢ = 8.8 nM) and H3R (KD = 31.2 nM)." [PMID:41616703]; target: "Among them, compound 67 demonstrated high binding affinity for both σ1R (Kᵢ = 8.8 nM) and H3R (KD = 31.2 nM)." [PMID:41616703]; developer: "Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, School of Pharmacy, Jiangsu Ocean University, Lianyungang, 222005, China." [PMID:41616703]; stage: "Compound 67 exhibited significant antinociceptive effects in the acetic acid-induced constriction test (ED50 = 0.18 mg/kg) and paclitaxel-induced neuropathic pain model (ED50 = 0.06 mg/kg), which demonstrated potency superior to that of marketed drug gabapentin." [PMID:41616703]