Drug intelligence / Profile preview

Jiangwei Anzhong Decoction

Development stage
Unknown
Lead developer
Beijing University of Chinese Medicine Fangshan Hospital
Administration
Oral
01

Overview

Jiangwei Anzhong Decoction is a Traditional Chinese Medicine (TCM) herbal formula developed by Fangshan Hospital of Beijing University of Chinese Medicine for the treatment of gastroesophageal reflux disease (GERD), specifically the 'liver stomach stasis heat' syndrome. The decoction is designed to regulate stomach qi and clear heat. Clinical evaluation involves assessing its impact on brain–gut peptides, such as 5-hydroxytryptamine (5-HT) and vasoactive intestinal peptide (VIP), which play roles in gastrointestinal motility and esophageal sphincter function. In clinical trials, it is compared against proton pump inhibitors like rabeprazole to evaluate its efficacy in reducing GERD symptoms, improving TCM syndrome scores, and alleviating comorbid anxiety and depression.

Other names
Jiangwei Anzhong Tang
02

Targets

5-HT (Serotonin receptors)

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