Drug intelligence / Profile preview

Jiangya Tongmai Formula

Development stage
Unknown
Lead developer
Xiyuan Hospital
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Jiangya Tongmai Formula is a Traditional Chinese Medicine (TCM) herbal composition developed by Xiyuan Hospital of the China Academy of Chinese Medical Sciences. It is primarily investigated for the treatment of H-type hypertension—a condition characterized by high blood pressure and elevated homocysteine levels—and associated carotid atherosclerosis. The formula is designed to exert antihypertensive effects while simultaneously addressing vascular remodeling and plaque formation. As a multi-herb preparation, it likely functions through synergistic mechanisms that modulate vascular resistance, reduce oxidative stress, and lower homocysteine concentrations, thereby mitigating the risk of cardiovascular events.

Other names
Jiangya Tongmai FangJiangya Tongmai GranuleJiangya Tongmai Granules
02

Targets

IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))

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