Jianpi Bushen formula

Jianpi Bushen formula (JPBS) is a Traditional Chinese Medicine (TCM) herbal preparation used to invigorate the spleen and tonify the kidney. It has demonstrated therapeutic effects across various conditions, including ulcerative colitis, colon cancer, osteoporotic fractures, chronic kidney disease (CKD) anemia, Alzheimer's disease, aromatase-inhibitor-associated bone loss, and gastric cancer. Its mechanisms of action are diverse, involving the promotion of intestinal stem cell differentiation, activation of the β-catenin signaling pathway, modulation of gut microbiota, anti-inflammatory effects, regulation of bone metabolism, and suppression of factors involved in pre-metastatic niche formation. JPBS has been investigated in both preclinical models and clinical trials, showing potential to improve chemotherapy completion rates in colon cancer patients and enhance various physiological parameters in other disease states.

Other names

Jianpi Bushen therapyQingchang Huashi Jianpi Bushen formulaQCHS_JPBS formula