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Jianpi Bushen Sequential Formula
- Development stage
- Unknown
- Lead developer
- Xiyuan Hospital
- Administration
- Oral
01
Overview
Jianpi Bushen Sequential Formula (JBSF) is a Traditional Chinese Medicine (TCM) herbal protocol developed to mitigate the adverse effects of adjuvant chemotherapy in patients with colon cancer. The formula is designed based on the TCM principles of 'Jianpi' (strengthening the spleen) and 'Bushen' (tonifying the kidney) to address chemotherapy-induced nausea and vomiting (CINV) and myelosuppression. The 'sequential' nature of the formula typically involves administering specific herbal combinations timed to the phases of the chemotherapy cycle (such as the oxaliplatin and capecitabine/CAPEOX regimen). Clinical research, including a multi-center randomized controlled trial (NCT03716518), focuses on its ability to improve chemotherapy completion rates, reduce treatment toxicity, and extend the time to treatment failure by supporting the patient's gastrointestinal and hematological health during oncology treatment.
- Other names
- 健脾补肾序贯方Jianpi Bushen Sequential Decoction
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