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Jianpi Bushen Shengyang Granules is a Traditional Chinese Medicine (TCM) herbal formulation primarily developed for the treatment of cancer-related fatigue (CRF) and syndromes associated with Spleen and Kidney deficiency. The preparation is composed of several botanical extracts, including *Astragalus membranaceus*, *Codonopsis pilosula*, and *Atractylodes macrocephala*, which are traditionally used to tonify Qi and raise Yang energy. Mechanistically, the granules are thought to modulate the immune system, reduce inflammatory cytokine levels (such as IL-6 and TNF-α), and improve mitochondrial function to enhance energy metabolism. It is frequently utilized in integrative oncology settings in China to improve the quality of life and physical stamina of patients undergoing cytotoxic therapies.
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