Drug intelligence / Profile preview

Jianpi Huayu Jiedu

Development stage
Unknown
Lead developer
Jiangsu Provincial Hospital of Traditional Chinese Medicine
Administration
Oral
01

Overview

Jianpi Huayu Jiedu is a Traditional Chinese Medicine (TCM) herbal formula developed by the Affiliated Hospital of Nanjing University of Chinese Medicine. It is primarily investigated for its therapeutic potential in patients with colorectal cancer, specifically those exhibiting spleen deficiency syndrome following chemotherapy. The formula is designed to improve patient quality of life by modulating the intestinal microecology and enhancing immune function. Clinical research focuses on identifying key intestinal flora affected by the formula and clarifying the internal relationship between spleen deficiency and gut microbiota balance in the context of post-chemotherapy recovery.

Other names
Jianpi Huayu Jiedu formulaJianpi Huayu Jiedu decoction
02

Targets

SLC7A11 (Cystine-Glutamate Antiporter)PPARA (Peroxisome proliferator-activated receptor alpha)CYP1B1 (Cytochrome P450 1B1)GPX4 (Glutathione peroxidase 4)15-LOX (Lysyl Oxidase)CCNE1 (Cyclin E1)PPARG (Peroxisome proliferator-activated receptor gamma)

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