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Jianpi Jieyu Gao is a Traditional Chinese Medicine (TCM) herbal formulation developed by Xiyuan Hospital of the China Academy of Chinese Medical Sciences. It is primarily indicated for the treatment of mild to moderate major depressive disorder, specifically targeting the TCM patterns of heart-spleen deficiency and liver qi stagnation. The medication is prepared as a concentrated herbal paste (Gao Fang), a traditional dosage form used for sustained therapeutic effect. It has been evaluated in prospective, randomized, double-blind, placebo-controlled clinical trials (e.g., ChiCTR2200065205) to assess its impact on depressive and anxiety symptoms using scales such as the 17-item Hamilton Depression Rating Scale (HAMD-17) and the Hamilton Anxiety Rating Scale (HAMA).
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