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Jianpi Lishi Jiedu Decoction
- Development stage
- Unknown
- Lead developer
- Nanjing Hospital of Integrated Traditional Chinese and Western Medicine
- Administration
- Oral
01
Overview
Jianpi Lishi Jiedu Decoction is a Traditional Chinese Medicine (TCM) herbal formula developed by the Nanjing Hospital of Integrated Traditional Chinese and Western Medicine. It is primarily investigated for its potential to prevent the recurrence of colorectal adenomas following surgical resection (polypectomy). The formula's name reflects its TCM therapeutic principles: "Jianpi" (strengthening the spleen), "Lishi" (draining dampness), and "Jiedu" (detoxifying). In the context of colorectal adenoma, it is hypothesized to modulate the intestinal microenvironment, reduce chronic mucosal inflammation, and inhibit the pathways leading to neoplastic recurrence. The efficacy and safety of the decoction are being evaluated in randomized, double-blind, placebo-controlled clinical trials.
- Other names
- Jianpi Lishi Jiedu FormulaJianpi Lishi Jiedu Tang
02
Targets
IL-6 (Interleukin 6)JAK (Janus kinase family)STAT3 (Signal Transducer and Activator of Transcription 3)
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