Drug intelligence / Profile preview

jianpi qinghua formula

Development stage
Phase 1
Lead developer
Shuguang Hospital
Administration
Oral
01

Overview

Jianpi Qinghua Formula is a Traditional Chinese Medicine (TCM) herbal compound developed for the treatment of various chronic metabolic and gastrointestinal conditions, including type 2 diabetes mellitus, non-erosive reflux disease (NERD), and chronic kidney disease. The formula is based on the TCM principles of strengthening the spleen (Jianpi) and clearing heat/dampness (Qinghua). Clinical research, primarily conducted by Shuguang Hospital (affiliated with Shanghai University of TCM) and Xiyuan Hospital, has investigated its ability to modulate glucagon-like peptide-1 (GLP-1) concentrations in diabetic patients and its efficacy in reducing symptoms of NERD, potentially allowing for the tapering of proton pump inhibitor (PPI) therapy. It is typically administered orally as a decoction or in granule form.

Brand names
Jianpi Qinghua granules
Other names
Jianpi Qinghua FormulaJianpi Qinghua GranulesJianpi Qinghua DecoctionJian Pi Qing Ha GranulesSpleen-Strengthening Decoction
02

Targets

JUNB (Transcription factor JunB mRNA)FOS (Activator Protein 1)GLP1R (GLP-1R)

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