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jianpi qingwei
- Development stage
- Unknown
- Lead developer
- Xiyuan Hospital
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Jianpi Qingwei is a Traditional Chinese Medicine (TCM) formula developed by the Jiangsu Provincial Hospital of Integrated Chinese and Western Medicine, specifically designed to treat metabolic disorders such as type 2 diabetes mellitus and obesity. The formula's name reflects its therapeutic strategy: "Jianpi" (strengthening the spleen) and "Qingwei" (clearing stomach heat), addressing the TCM patterns of spleen deficiency and stomach fire often seen in metabolic syndrome. Its pharmacological effects include the stimulation of endogenous glucagon-like peptide-1 (GLP-1) secretion, enhancement of insulin sensitivity, and modulation of the gut microbiota to reduce metabolic endotoxemia and systemic inflammation. It is typically administered as oral granules and has been evaluated in clinical trials for its efficacy in weight reduction and glycemic control.
- Brand names
- Jianpi Qingwei Granules
- Other names
- Jianpi Qingwei FormulaJianpi Qingwei Decoction健脾清胃方
02
Targets
GLP1R (GLP-1R)INSR (Insulin receptor)
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