Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Jianpi Qushi Heluo Fang
- Development stage
- Preclinical
- Administration
- Oral
01
Overview
Jianpi Qushi Heluo Fang (JQHF) is an empirical traditional Chinese medicine (TCM) prescription used clinically in China for the treatment of membranous nephropathy (MN), particularly idiopathic or primary membranous nephropathy. The formula typically contains a combination of herbal ingredients such as Huang Qi (Astragalus membranaceus), Dang Shen (Codonopsis pilosula), Fu Ling (Poria cocos), and others. Preclinical studies suggest that JQHF alleviates renal damage by reducing proteinuria, improving serum albumin levels, and modulating immune function. Mechanistically, it appears to protect against mitochondrial dysfunction and apoptosis in kidney tissue by upregulating autophagy-related pathways—specifically the PINK1/Parkin pathway—and regulating proteins involved in mitochondrial health and cell survival. The exact mechanism remains under investigation but involves modulation of oxidative stress, immune complex deposition, and cellular homeostasis[2][3][6][7].
- Brand names
- Jian Pi Qu Shi Formula
- Other names
- Jianpi Qushi Heluo FormulaJianpi-Qushi-Heluo formulaJQHF
02
Targets
PINK1 (PTEN-induced kinase 1)
Beyond the preview
Go deeper on Jianpi Qushi Heluo Fang.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Jianpi Qushi Heluo Fang.