Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Jianpi Sanjie Formula
- Development stage
- Unknown
- Lead developer
- Shanghai University of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
Jianpi Sanjie Formula (JPSJF) is a Traditional Chinese Medicine (TCM) herbal decoction primarily utilized as an adjuvant therapy for gastrointestinal malignancies, including gastric and colorectal cancers. The formula is designed based on the TCM principles of strengthening the spleen (Jianpi) to bolster the body's 'Zheng Qi' (vital energy) and resolving hard masses or nodules (Sanjie) to counteract tumor progression. Mechanistically, JPSJF has been shown to inhibit tumor cell proliferation, migration, and invasion by modulating various signaling pathways, such as the PI3K/Akt and Wnt/β-catenin pathways. It is also reported to regulate the tumor microenvironment, enhance immune function by balancing T-lymphocyte subsets, and reduce the systemic toxicity and side effects associated with conventional chemotherapy.
- Other names
- Jianpi Sanjie Decoction健脾散结方Jianpi Sanjie Tang
02
Targets
AKT (RAC-alpha serine/threonine-protein kinase)CTNNB1 (Beta-catenin)PI3K (Phosphoinositide-3-kinase regulatory subunit 6)VEGFA (Vascular endothelial growth factor A)
Beyond the preview
Go deeper on Jianpi Sanjie Formula.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Jianpi Sanjie Formula.