jianpi shengsui

Jianpi Shengsui (often referred to as Jian Pi Sheng Sui Gao or JPSSG) is a traditional Chinese medicine (TCM) herbal formulation used primarily for the management of cancer-related fatigue (CRF), especially in patients undergoing chemotherapy. The formula is typically prepared as a paste and consists of 17 different herbs and animal-derived ingredients, including Chinemys reevesii (Asian pond turtle), Cervus elaphus (deer antler), Ligustrum lucidum, Codonopsis pilosula, Hordeum vulgare (barley), Citrus reticulata (tangerine peel), Lycium barbarum (goji berry), among others[9][1][2]. Mechanistically, JPSSG has been shown in preclinical studies to alleviate skeletal myoblast cell apoptosis, reduce oxidative stress, and improve mitochondrial function—effects believed to be mediated via the AMPK-SIRT1-PGC-1α signaling pathway[1][5]. Clinically, it has demonstrated efficacy in reducing fatigue scores and improving quality of life for cancer patients post-chemotherapy[2][9]. The formula reflects TCM principles of "strengthening the spleen" and "replenishing essence," aiming to restore Qi and support recovery from deficiency syndromes associated with chronic illness or aggressive medical treatments.

Other names

Jian Pi Sheng Sui GaoJPSSGJianpi Shengsui Herbal Paste