Drug intelligence / Profile preview

Jianpi Yanggan Tang

Development stage
Unknown
Administration
Oral
01

Overview

Jianpi Yanggan Tang (健脾养肝汤), meaning "Spleen-Strengthening and Liver-Nourishing Soup," is a traditional Chinese medicine (TCM) herbal formula primarily used as a dietary therapy. It is composed of several herbs and food ingredients, including Chinese Yam, Lotus Seed, Red Date, Goji Berry, Angelica Sinensis, and Codonopsis Pilosula. In TCM, its main actions are to strengthen the spleen (健脾) and nourish the liver (养肝), aiming to improve digestive function, support liver health, and enhance overall well-being. It is traditionally indicated for conditions associated with spleen deficiency and liver imbalance, such as fatigue, poor appetite, and certain liver-related issues. While specific molecular mechanisms for this exact formulation are not extensively documented in Western scientific literature, related "Jianpi Yanggan" formulas have been investigated for effects such as promoting mitophagy, inhibiting inflammatory pathways (e.g., PI3K/AKT/mTOR), and ameliorating hepatocyte injury.

Other names
健脾养肝汤Spleen-Strengthening and Liver-Nourishing Soup
02

Targets

AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)ESR1 (ERα)EGFR T790M (Epidermal growth factor receptor T790M mutant)

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