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Jianpi Yishen Huazhuo granules is a Traditional Chinese Medicine (TCM) formulation developed by Xiyuan Hospital of the China Academy of Traditional Chinese Medicine for the treatment of vascular dementia. The formulation is designed to address the TCM syndromes of spleen–kidney deficiency and phlegm–blood stasis, which are hypothesized to contribute to the pathogenesis of cognitive impairment following cerebrovascular events. By tonifying the spleen and kidney and promoting the resolution of phlegm and blood stasis, the granules aim to improve cognitive performance and daily functioning. It is currently undergoing Phase 2 clinical evaluation in China to establish its safety and therapeutic efficacy.
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