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Jianpi Yiwei Formula is a traditional Chinese medicine (TCM) herbal combination designed to "invigorate the spleen" and "benefit the stomach," primarily used for digestive disorders associated with spleen deficiency in TCM theory. The formula typically contains a blend of herbs such as Atractylodes macrocephala (Bai Zhu), Poria cocos (Fu Ling), Codonopsis pilosula (Dang Shen), Glycyrrhiza uralensis (Gan Cao), Citrus reticulata (Chen Pi), and others. It is commonly used to support healthy digestion, improve appetite, reduce bloating and loose stools, and enhance overall gastrointestinal function. Mechanistically, it is believed to regulate gastrointestinal motility and secretion through multi-target actions including modulation of gut microbiota composition and anti-inflammatory effects. Modern studies suggest that similar formulas can modulate tryptophan metabolism pathways and aryl hydrocarbon receptor signaling in animal models[3][6][8]. The formula is widely manufactured by companies specializing in TCM products.
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