Drug intelligence / Profile preview

Jianpi Yiwei Formula

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Jianpi Yiwei Formula is a traditional Chinese medicine (TCM) herbal combination designed to "invigorate the spleen" and "benefit the stomach," primarily used for digestive disorders associated with spleen deficiency in TCM theory. The formula typically contains a blend of herbs such as Atractylodes macrocephala (Bai Zhu), Poria cocos (Fu Ling), Codonopsis pilosula (Dang Shen), Glycyrrhiza uralensis (Gan Cao), Citrus reticulata (Chen Pi), and others. It is commonly used to support healthy digestion, improve appetite, reduce bloating and loose stools, and enhance overall gastrointestinal function. Mechanistically, it is believed to regulate gastrointestinal motility and secretion through multi-target actions including modulation of gut microbiota composition and anti-inflammatory effects. Modern studies suggest that similar formulas can modulate tryptophan metabolism pathways and aryl hydrocarbon receptor signaling in animal models[3][6][8]. The formula is widely manufactured by companies specializing in TCM products.

Brand names
Jian Pi PianJian Pi WanSpleenVigor
Other names
Jian Pi Yi Wei Fang健脾益胃方Jian Pi PianSpleenVigorJian Pi Wan
02

Targets

AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)TP53 (Cellular Tumor Antigen p53 R175H)

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