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Jianpizhixie is a Traditional Chinese Medicine (TCM) formulation developed by Beijing Ditan Hospital specifically for the management of chronic diarrhea in patients with HIV/AIDS. The drug is designed based on the TCM therapeutic principle of "strengthening the spleen and arresting diarrhea" (Jianpi Zhixie), addressing the underlying gastrointestinal dysfunction and "spleen deficiency" commonly observed in immunocompromised individuals. Typically administered as an oral granule, the formulation consists of a blend of herbal ingredients such as *Codonopsis pilosula*, *Atractylodes macrocephala*, and *Poria cocos*, which are known for their anti-diarrheal and immunomodulatory properties. Clinical studies conducted at Beijing Ditan Hospital have evaluated its efficacy in reducing stool frequency, improving stool consistency, and enhancing the overall quality of life for AIDS patients suffering from opportunistic gastrointestinal infections or medication-related side effects.
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