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Jiawei Bushen Yiqi Granules
- Development stage
- Unknown
- Lead developer
- Huashan Hospital
- Administration
- Oral
01
Overview
Jiawei Bushen Yiqi (JWBY) granules, also known as Modified Jiawei Bushen Yiqi Formula (MBYF), is a Traditional Chinese Medicine (TCM) herbal formulation composed of five herbs, including *Epimedium brevicornu* Maxim (Herba Epimedii) and *Astragalus membranaceus*. It is primarily investigated for the treatment of chronic obstructive pulmonary disease (COPD) and lung cancer. The formula is often used as an adjunct therapy to systemic glucocorticoids for acute exacerbations of COPD or as an add-on to inhaled corticosteroids like budesonide/formoterol. Its mechanism of action involves the inhibition of neutrophil chemotaxis and the IL-17 signaling pathway, which helps reduce pulmonary inflammation and airway remodeling. Clinical research has been conducted at institutions such as Huashan Hospital affiliated with Fudan University.
- Other names
- Modified Jiawei Bushen Yiqi Formula加味补肾益气颗粒
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