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jiawei taohong siwu decoction
- Development stage
- Unknown
- Lead developer
- Shuguang Hospital
- Administration
- Oral
01
Overview
Jiawei Taohong Siwu Decoction is a modified Traditional Chinese Medicine (TCM) herbal formula based on the classic Taohong Siwu Decoction (Peach Kernel and Safflower Four-Substance Decoction). It is primarily investigated for its potential in treating severe non-proliferative diabetic retinopathy (NPDR). The base formula, Taohong Siwu, is traditionally used to "activate blood and resolve stasis," a therapeutic principle aimed at improving microcirculation and reducing vascular permeability. The "Jiawei" (modified) version typically includes additional herbs tailored to the specific pathology of diabetic complications, such as those targeting Qi or Yin deficiency. In clinical research, it is often evaluated as an adjuvant therapy alongside standard treatments like laser photocoagulation to mitigate retinal ischemia and hypoxia-induced damage.
- Brand names
- Jiawei Taohong Siwu Decoction
- Other names
- Modified Taohong Siwu DecoctionJiawei Taohong Siwu Tang
02
Targets
BCL-2 (BCL-2 family)IL-6 (Interleukin 6)NOS2 (Nitric Oxide Synthase 2)
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