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Jiawei Tongbian Decoction
- Development stage
- Unknown
- Lead developer
- Nanjing University of Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Jiawei Tongbian Decoction is a Traditional Chinese Medicine (TCM) herbal formula developed for the treatment of functional constipation, particularly when accompanied by comorbid psychological symptoms such as anxiety and depression. As a 'Jiawei' (modified) formula, it typically consists of a base set of herbs known for promoting bowel movements (such as those that moisten the intestines or stimulate peristalsis) supplemented with additional ingredients intended to regulate Qi and soothe the liver to address emotional distress. The decoction is administered orally and is being evaluated for its ability to improve both gastrointestinal transit and the psychological well-being of patients, potentially acting through the brain-gut axis.
- Other names
- Jiawei Tongbian TangModified Tongbian Decoction
02
Targets
5-HT (Serotonin receptors)
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